Hitoshi Higuchi Selected Research

15-deoxy-delta(12,14)-prostaglandin J2

2/2021

Dexmedetomidine inhibits LPS-induced inflammatory responses through peroxisome proliferator-activated receptor gamma (PPARγ) activation following binding to α2 adrenoceptors.

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Hitoshi Higuchi Research Topics

Disease

6	Intellectual Disability (Idiocy) 09/2021 - 12/2011
5	Inflammation (Inflammations) 02/2021 - 06/2008
4	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2022 - 01/2009
4	Epilepsy (Aura) 01/2020 - 01/2009
2	Hypoxia (Hypoxemia) 11/2022 - 09/2021
2	Vomiting 12/2020 - 01/2012
2	Postoperative Pain 01/2020 - 10/2015
2	Body Weight (Weight, Body) 01/2020 - 01/2016
2	Pain (Aches) 01/2019 - 01/2017
2	Neuralgia (Stump Neuralgia) 01/2019 - 10/2015
2	Hypertension (High Blood Pressure) 05/2016 - 01/2014
2	Hypotension (Low Blood Pressure) 01/2014 - 05/2004
1	Hypercapnia 11/2022
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 04/2022
1	Deglutition Disorders (Dysphagia) 04/2022
1	Airway Obstruction (Choking) 09/2021
1	Hyperoxia 02/2019
1	Cognitive Dysfunction 10/2018
1	Hypertrophy 01/2018
1	Retinal Diseases 11/2016
1	Hyperalgesia 10/2015
1	Edema (Dropsy) 02/2014
1	Tachycardia (Tachyarrhythmias) 01/2014
1	Tooth Abnormalities 01/2012
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2012
1	Hypersensitivity (Allergy) 01/2011
1	Laryngismus (Laryngospasm) 10/2010
1	Brain Ischemia (Cerebral Ischemia) 01/2009
1	Carcinoma (Carcinomatosis) 01/2009
1	Sepsis (Septicemia) 06/2008
1	Delirium 06/2008
1	Heart Arrest (Cardiac Arrest) 03/2007

Drug/Important Bio-Agent (IBA)

5	Propofol (Diprivan)FDA LinkGeneric 01/2020 - 03/2007
3	Midazolam (Versed)FDA LinkGeneric 05/2016 - 03/2007
3	Anticonvulsants (Antiepileptic Drugs)IBA 02/2016 - 01/2012
2	Oxygen (Dioxygen)IBA 11/2022 - 02/2019
2	Anesthetics (Anesthetic Agents)IBA 09/2021 - 01/2020
2	ProstaglandinsIBA 02/2021 - 05/2004
2	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2020 - 01/2017
2	CarrageenanIBA 01/2019 - 02/2014
2	Interleukin-6 (Interleukin 6)IBA 10/2018 - 05/2004
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 05/2010
2	Dexmedetomidine FDA Link 10/2015 - 02/2014
2	IronIBA 01/2011 - 01/2009
2	CytokinesIBA 06/2008 - 05/2004
1	Capsaicin (Zostrix)FDA Link 04/2022
1	15-deoxy-delta(12,14)-prostaglandin J2IBA 02/2021
1	Prostaglandin D2IBA 02/2021
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 02/2021
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 02/2021
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2020
1	Fentanyl (Sublimaze)FDA LinkGeneric 01/2020
1	MucinsIBA 02/2019
1	Amylases FDA Link 02/2019
1	Pilocarpine (Ocusert)FDA LinkGeneric 02/2019
1	Salivary Proteins and PeptidesIBA 02/2019
1	Cyclic NucleotidesIBA 01/2019
1	IvabradineIBA 01/2019
1	CollagenIBA 01/2018
1	SteroidsIBA 01/2017
1	Flurbiprofen (Froben)FDA LinkGeneric 01/2017
1	Analgesics (Analgesic Drugs)IBA 01/2017
1	Betamethasone (Celestone)FDA Link 01/2017
1	Retinaldehyde (Retinal)IBA 11/2016
1	Anti-Anxiety Agents (Anxiolytics)IBA 05/2016
1	BarbituratesIBA 01/2015
1	BenzodiazepinesIBA 01/2015
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2014
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 02/2014
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2014
1	Antipsychotic Agents (Antipsychotics)IBA 01/2014
1	Propranolol (Inderal)FDA LinkGeneric 01/2014
1	Epinephrine (Adrenaline)FDA LinkGeneric 01/2014
1	Chlorpromazine (Thorazine)FDA Link 01/2014
1	Pharmaceutical PreparationsIBA 01/2012
1	EnzymesIBA 01/2012
1	Local AnestheticsIBA 01/2011
1	ferric nitrilotriacetateIBA 01/2009
1	LipopolysaccharidesIBA 06/2008
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 06/2008
1	Heme Oxygenase-1IBA 06/2008
1	Isoflurane FDA LinkGeneric 05/2004

Therapy/Procedure

4	General Anesthesia 01/2017 - 10/2010
3	Therapeutics 11/2022 - 01/2014
3	Anesthesia 12/2020 - 05/2004
2	Drug Therapy (Chemotherapy) 01/2020 - 01/2012
1	Deep Sedation 09/2021
1	Cannula 09/2021
1	Osteotomy 01/2020
1	Subcutaneous Injections 01/2019
1	Intravenous Anesthesia 06/2012
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2012
1	Local Anesthesia 01/2011
1	Controlled Hypotension 05/2004
1	Oral Surgery (Maxillofacial Surgery) 05/2004